The Pathogenesis of Topical Steroid Acne

The pathogenesis of acne.

Acne vulgaris is a multifactorial disease of as yet incompletely elucidated etiology and pathogenesis. The following have been identified as the most significant factors: follicular hyperkeratosis, increased sebum secretion, Propionibacterium (P.) acnes, and inflammation. Increased sebum production and follicular hyperkeratosis result in the development of microcomedones, and changes in follicu...

New Topical Acne Treatment

Comparison of Topical Azithromycin and Clindamycin in the Treatment of Mild to Moderate Acne Vulgaris

Background: Acne vulgaris is the most common cause for dermatology visits and is one of the most common diseases that people experience during their lives. Although this disease is not life-threatening, it may affect the life quality of the patients because of developing irreparable complications on the skin. Dermatologists are in agreement about topical treatment in the mild to moderate acne v...

Rediscovering Topical Antimicrobial Therapy for Acne Vulgaris

Practical Dermatology 55 G iven that 40 to 50 million people in the US are affected by acne vulgaris, dermatologists are comfortable with its management and familiar with the range of available topical and systemic treatment options. Yet familiarity with the condition can lead clinicians to overlook new treatment options or emerging evidence about acne and the experiences of affected patients. ...

Pathogenesis of acne vulgaris: recent advances.

Acne vulgaris is the most common disorder seen in ambulatory dermatology practice. Acne causes significant morbidity and the direct costs associated with it exceed $2.2 billion per year in the United States (U.S.). The pathogenesis is multifactorial, and our understanding of the mechanisms involved in the development of acne lesions has improved with time. Follicular hyperkeratinization, sebum ...